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ea0037ep560 | Obesity and cardiovascular endocrinology | ECE2015

Galectin-3 and fibulin-1 in systolic heart failure patients with and without diabetes: relation to glucose metabolism and left ventricular contractile reserve

Holmager Pernille , Egstrup Michael , Gustafsson Ida , Schou Morten , Dahl Jordi , Ramussen Lars Melholt , Moller Jacob , Tuxen Christian , Faber Jens , Kistorp Caroline

Aims: Diabetic patients with heart failure (HF) have an adverse prognosis, which could be linked with reduced left ventricular (LV) contractile reserve. Galectin-3 (Gal-3) and fibulin-1 are potential biomarkers of fibrosis. The aims were to evaluate the impact of DM on Gal-3 and fibulin-1 levels and the association to LV contractile reserve in HF patients with and without diabetes (DM).Methods and results: From an out-patient HF clinic 155 patients with ...

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Endocrine Abstracts

Galectin-3 and fibulin-1 in systolic heart failure patients with and without diabetes: relation to glucose metabolism and left ventricular contractile reserve

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